Which class of antihypertensive is contraindicated in asthma?

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Multiple Choice

Which class of antihypertensive is contraindicated in asthma?

Beta-blockers are contraindicated in asthma because they can block beta-2 receptors in the airway, which normally promote bronchodilation. When these receptors are blocked, bronchial smooth muscle tends to constrict, making asthma symptoms worse and increasing the risk of bronchospasm. This is especially true for nonselective beta-blockers that hit both beta-1 (heart) and beta-2 (lung) receptors. Cardioselective beta-1 blockers spare the lungs more, but they’re still used with caution in asthma. The other antihypertensive classes listed don’t directly suppress bronchial relaxation and are generally acceptable choices in patients with asthma when clinically appropriate.

Beta-blockers are contraindicated in asthma because they can block beta-2 receptors in the airway, which normally promote bronchodilation. When these receptors are blocked, bronchial smooth muscle tends to constrict, making asthma symptoms worse and increasing the risk of bronchospasm. This is especially true for nonselective beta-blockers that hit both beta-1 (heart) and beta-2 (lung) receptors. Cardioselective beta-1 blockers spare the lungs more, but they’re still used with caution in asthma. The other antihypertensive classes listed don’t directly suppress bronchial relaxation and are generally acceptable choices in patients with asthma when clinically appropriate.

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