Which class can treat hypertension and BPH?

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Multiple Choice

Which class can treat hypertension and BPH?

Explanation:
Alpha-adrenergic blockers have dual effects: they relax smooth muscle in both the vascular system and the urinary tract. By blocking alpha-1 receptors, they reduce vascular resistance, lowering blood pressure, and at the same time relax the smooth muscle in the bladder neck and prostatic urethra, improving obstruction from benign prostatic hyperplasia. That makes this class capable of treating both hypertension and BPH. In contrast, ACE inhibitors lower blood pressure by interfering with the renin-angiotensin system but don’t relieve BPH symptoms. Spironolactone is a potassium-sparing diuretic with antiandrogen effects that doesn’t address BPH, and hydralazine lowers BP through arteriolar dilation without affecting prostatic smooth muscle.

Alpha-adrenergic blockers have dual effects: they relax smooth muscle in both the vascular system and the urinary tract. By blocking alpha-1 receptors, they reduce vascular resistance, lowering blood pressure, and at the same time relax the smooth muscle in the bladder neck and prostatic urethra, improving obstruction from benign prostatic hyperplasia. That makes this class capable of treating both hypertension and BPH. In contrast, ACE inhibitors lower blood pressure by interfering with the renin-angiotensin system but don’t relieve BPH symptoms. Spironolactone is a potassium-sparing diuretic with antiandrogen effects that doesn’t address BPH, and hydralazine lowers BP through arteriolar dilation without affecting prostatic smooth muscle.

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