Which artery supplies the anterior wall and is commonly occluded in anterior wall MI?

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Understanding which myocardial regions each artery nourishes helps explain why an anterior wall MI points to the left anterior descending artery. The left anterior descending artery travels in the anterior interventricular groove and supplies the majority of the anterior left ventricular wall and the anterior portion of the interventricular septum. Because it covers such a large territory, occlusion of this artery often causes a large anterior wall infarct, commonly presenting with ST elevations in the precordial leads (V1–V4) on ECG. The other major arteries supply different regions: the right coronary artery typically feeds the inferior wall (and sometimes the posterior), the left circumflex artery supplies the lateral wall, and the posterior descending artery supplies the posterior region. Thus, the artery that explains an anterior wall MI is the left anterior descending artery.