What is the therapeutic INR range after mechanical valve replacement?

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Multiple Choice

What is the therapeutic INR range after mechanical valve replacement?

Explanation:
After a mechanical valve is placed, lifelong anticoagulation with warfarin is necessary to prevent valve thrombosis and embolic stroke. The intensity of anticoagulation is tracked by the INR. For most adults with a mechanical valve, the therapeutic INR range is about 2.5 to 3.5. This range balances preventing clot formation on the prosthetic valve with keeping bleeding risk manageable. Lower ranges would leave the valve susceptible to thrombosis, while higher ranges—like 4.0 to 5.0—raise the risk of serious bleeding. INR is monitored regularly and adjusted to stay within this target.

After a mechanical valve is placed, lifelong anticoagulation with warfarin is necessary to prevent valve thrombosis and embolic stroke. The intensity of anticoagulation is tracked by the INR. For most adults with a mechanical valve, the therapeutic INR range is about 2.5 to 3.5. This range balances preventing clot formation on the prosthetic valve with keeping bleeding risk manageable. Lower ranges would leave the valve susceptible to thrombosis, while higher ranges—like 4.0 to 5.0—raise the risk of serious bleeding. INR is monitored regularly and adjusted to stay within this target.

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