Main etiologies of aortic stenosis include:

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Multiple Choice

Main etiologies of aortic stenosis include:

Aortic stenosis most commonly results from calcific degeneration of the valve as people age, and when a congenital bicuspid aortic valve is present, this degeneration happens earlier. The combination of a congenital bicuspid valve and calcification of the valve from degenerative/atherosclerotic processes (often linked with CAD) best captures these main pathways. Rheumatic disease can cause aortic stenosis, but it is less common today and usually affects multiple valves (often with the mitral). Mitral valve prolapse and Marfan syndrome are not typical primary causes of isolated aortic stenosis.

Aortic stenosis most commonly results from calcific degeneration of the valve as people age, and when a congenital bicuspid aortic valve is present, this degeneration happens earlier. The combination of a congenital bicuspid valve and calcification of the valve from degenerative/atherosclerotic processes (often linked with CAD) best captures these main pathways. Rheumatic disease can cause aortic stenosis, but it is less common today and usually affects multiple valves (often with the mitral). Mitral valve prolapse and Marfan syndrome are not typical primary causes of isolated aortic stenosis.

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