Hypertrophic cardiomyopathy is characterized by which combination?

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Multiple Choice

Hypertrophic cardiomyopathy is characterized by which combination?

Hypertrophic cardiomyopathy causes thickened ventricular muscle that makes the ventricle stiff and less able to fill during diastole. The hallmark is myocardial hypertrophy with abnormal diastolic filling, often with preserved or even increased systolic function early on. This diastolic dysfunction due to the noncompliant ventricle best fits the description of thickened myocardium paired with impaired filling. Systolic dysfunction with dilated chambers is typical of dilated cardiomyopathy, not HCM. Pericardial effusion involves fluid around the heart, not intrinsic myocardial hypertrophy. Myocardial infarction results from ischemic injury with wall motion abnormalities, not the characteristic diastolic dysfunction from a thick, stiff ventricle.

Hypertrophic cardiomyopathy causes thickened ventricular muscle that makes the ventricle stiff and less able to fill during diastole. The hallmark is myocardial hypertrophy with abnormal diastolic filling, often with preserved or even increased systolic function early on. This diastolic dysfunction due to the noncompliant ventricle best fits the description of thickened myocardium paired with impaired filling.

Systolic dysfunction with dilated chambers is typical of dilated cardiomyopathy, not HCM. Pericardial effusion involves fluid around the heart, not intrinsic myocardial hypertrophy. Myocardial infarction results from ischemic injury with wall motion abnormalities, not the characteristic diastolic dysfunction from a thick, stiff ventricle.

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