Blockage of which artery causes an anterior wall myocardial infarction?

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The front (anterior) wall of the left ventricle is supplied mainly by the left anterior descending artery. When this vessel becomes occluded, blood flow to the anterior wall—and the anterior portion of the interventricular septum—drops, leading to an anterior wall myocardial infarction. The LAD travels along the anterior interventricular groove and sends septal perforators and diagonal branches to perfuse these regions; occlusion here often causes a large anterior STEMI with ST elevations in the anterior leads (V1–V4). The right coronary artery mainly supplies the inferior wall (and, via the posterior descending artery in many people, the posterior/inferior regions), while the left circumflex artery supplies the lateral (and sometimes anterolateral) wall. Thus, blockage of the left anterior descending artery best explains an anterior wall MI.